Weighing the Risks of Celebrex

Ibuprofen tablets
Photo credit: Wikimedia / public domain
Non-steroidal anti-inflammatory medicines (NSAIDs) have been around since the 1960s. They include ibuprofen (Advil, Motrin), naproxen (Aleve), meloxicam (Mobic), diclofenac (Voltaren) and over a dozen others. NSAIDs are used to treat pain, decrease fever, and decrease inflammation. They are prescribed over 100 million times annually in the US. Naproxen and ibuprofen are also available over the counter. NSAIDs were a boon compared to the medications that were available before them. They ar...

Less Invasive Method of Replacing Aortic Valves

The Hufnagel Heart Valve developed in the 1950s.
Credit: National Museum of Health and Medicine / Wikipedia
The aortic valve is the valve that allows blood out of the heart into the aorta, but not back. As people get older it’s not uncommon for the aortic valve to accumulate calcium deposits, stiffen, and not open as widely. This condition is called aortic stenosis. As the aortic valve narrows, it impairs the blood flow through it. Patients can develop heart failure, lightheadedness, chest pain, and fainting. There are no effective medications for aortic stenosis. Until several years ago the only ...

There Has Never Been a Better Time to Have Diabetes

The danger of diabetes is not only the immediate risk of very high blood sugar. Diabetes also has many dreaded long-term complications. (In this post I am referring to both type 1 and type 2 diabetes mellitus. For an explanation of the differences between these two very different diseases see the first half of this post.) Diabetes greatly increases the risk of stroke, heart attack, and amputation. In the US it is the leadin...

What We Don’t Know About Eating Fat

Most humans have spent most of human history nearly starving to death. So it’s no surprise that we spend a lot of time thinking about food. And it’s no surprise that food has acquired cultural, social, and religious significance in almost every society. Because food is so important, and because it’s nearly impossible for us not to ascribe powerful effects to anything important to us, every society imbues special health properties to various foods. From believing that some foods are aphrod...

On Stinting On Stents

Former President George W. Bush underwent an angioplasty this week, and the details sparked a public debate about the controversies of heart disease treatments. His spokesman stated that he underwent a routine physical exam and had no symptoms of heart disease. A stress test showed EKG changes and a CT angiogram found a blocked artery. He was transferred to another hospital and underwent an angioplasty, a procedure in which a stent (a wire mesh tube) is inserted into the blocked artery an...

Little Evidence that Low-Salt Diet Prevents Heart Disease

We know that people with high cholesterol have a higher risk for strokes and heart attacks than people with low cholesterol. So if a medicine lowers cholesterol it should also lower the frequency of strokes and heart attacks too. Right? Not necessarily. Estrogen lowers cholesterol and doesn't lower stroke or heart attack risk. We also know that people with high blood pressure have a higher risk for strokes and heart attacks. Does that mean that a food that elevates blood pressure increases str...

Supplementing Mediterranean Diet with Olive Oil or Nuts Decreases Stroke Risk

What is a Mediterranean diet? I had always believed that it involves eating shawarma three times a day while sitting on a beach in Tel Aviv, just because that’s my diet when I visit the Mediterranean. I was astounded to learn that this is not the case. A Mediterranean diet includes a lot of fruits, nuts, vegetables, olive oil, and cereals. It includes moderate intake of fish and poultry, and very little dairy, red meat, and sweets. Wine is included in moderation and consumed with meal...

Newsflash: Smoking is Very Unhealthy

I have shocking news. Smoking is very very bad for you. In 1964 the US Surgeon General issued a report summarizing the known adverse health effects of smoking. At that time about 40% of American adults smoked. A widespread campaign followed informing Americans about the link between smoking and lung cancer, emphysema, stroke, and heart attacks. Federal law required the placement of health warnings on cigarette packages, and school children all learned about the adverse health effects of smoki...